Chuck Close is an amazing character. He suffered a partial stroke in 1989 and his description of the process he underwent to regain the ability to paint and the processes he uses everyday to create his painting is really interesting. He approaches paintings on very long timelines (some images take 14 months to complete) and the way he keeps motivated and satisfied with his slow progress is a lesson for everyone. It's a useful reassessment of the power of small tasks done often.
You can listen to the NPR 1998 radio interview here.
Here is a CBS clip of Chuck Close working along with an article. (Thanks Edge3Sixty for the link)